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陈敏,博士、讲师、硕士生导师
联系方式
地址:扬州市华扬西路196号扬州大学环境学科与工程学院
邮编: 225127
电话:0514-89795882
E-mail:chenmin@yzu.edu.cn
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个人简要经历与学历
2003.9-2008.6,衡阳师范学院,化学与材料科学学院,学士
2008.9-2013.6,中国海洋大学,医药学院,博士
2009.3-2011.3,中山大学,化学与化工学院,联合培养研究生
2013.9-2015.7,中国海洋大学,海洋生命学院,博士后
2015.8-至今,扬州大学,bet28365-365,讲师
主要研究方向
1. 海洋真菌次级代谢产物化学多样性及药理活性研究。
2. 对具有重要药理活性的海洋天然产物进行结构修饰,探讨构效关系,为新药研发提供药物先导化合物。
主要讲授课程
1. 海洋调查方法
2. 海洋法
科研情况
近五年来承担了中国博士后科学基金、江苏省高校自然科学研究面上项目等多项课题,发现新化合物40余个,发表研究论文30余篇,其中在Journal of Natural Products、Marine Biotechnology、Marine Drugs、Tetrahedron、Chemistry & Biodiversity、Natural Product Research等知名学术期刊上发表SCI收录的研究论文20余篇,其中第一作者或通讯作者15篇,单篇最高他引20余次,H因子为8;申请发明专利10余项,已授权5项。
代表性论文
1.Topsensterols A?C, Cytotoxic Polyhydroxylated Sterol Derivatives from a Marine Sponge Topsentia sp. Marine Drugs, 2016, 14(8), 146.
2.DNA Methyltransferase Inhibitor Induced Fungal Biosynthetic Products: Diethylene Glycol Phthalate Ester Oligomers from the Marine-Derived Fungus Cochliobolus lunatus. Marine Biotechnology, 2016, 18(3), 409-417.
3.Cytotoxic 19-oxygenated steroids from the South China Sea gorgonian, Pacifigorgia senta. Natural Product Research 2016, 30(12), 1431-1435.
4.Bioactive Diphenyl Ether Derivatives from a Gorgonian-Derived Talaromyces sp. Fungus. Chemistry & Biodiversity 2015, 12, (3), 443-450.
5.Bioactive Steroid Derivatives and Butyrolactone Derivatives from a Gorgonian-Derived Aspergillus sp. Fungus. Chemistry & Biodiversity 2015, 12, (9), 1398-1406.
6.Anti-Respiratory Syncytial Virus Prenylated Dihydroquinolone Derivatives from the Gorgonian-Derived Fungus Aspergillus sp. XS-20090B15. Journal of Natural Products 2014, 77, (12), 2720-2724.
7.Lumazine Peptides Penilumamides B–D and the Cyclic Pentapeptide Asperpeptide A from a Gorgonian-Derived Aspergillus sp. Fungus. Journal of Natural Products 2014, 77, (7), 1601-1606.
8.Dihydroisocoumarin derivatives with antifouling activities from a gorgonian-derived Eurotium sp. fungus. Tetrahedron 2014, 70, (47), 9132-9138.
9.Nucleoside derivatives from the marine-derived fungus Aspergillus versicolor. Natural Product Research 2014, 28, (12), 895-900.
10.Bioactive Indole Alkaloids and Phenyl Ether Derivatives from a Marine-Derived Aspergillus sp. Fungus. Journal of Natural Products 2013, 76, (4), 547–553.
授权专利
1.一种喹啉酮生物碱的制备方法与作为环境友好型海洋生物防污剂的应用,ZL201310165301.5
2.一种联苯醚化合物的制备方法与作为天然海洋生物防污剂的应用,ZL201310083760.9
3.一种木脂素化合物及其制备方法与作为天然海洋生物防污剂的应用,ZL201310165302.X
4.一种溴代联苯醚衍生物的制备方法与作为抗菌剂的应用,ZL201310053904.6
5.一种异香豆素类化合物的制备方法与作为抗菌剂的应用,ZL201310429589.2